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High-throughput fingerprinting of human pluripotent stem cell factor responsiveness and lineage induction bias
Populations of cells create local environments that lead to emergent heterogeneity. This is particularly evident in human pluripotent stem cells (hPSCs) where microenvironmental heterogeneity limits cell fate control. We have developed a high-throughput platform to screen hPSCs in configurable micro...
Autores principales: | Nazareth, Emanuel J.P., Ostblom, Joel E.E., Lücker, Petra B., Shukla, Shreya, Alvarez, Manuel M., Oh, Steve K.W., Yin, Ting, Zandstra, Peter W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061564/ https://www.ncbi.nlm.nih.gov/pubmed/24141495 http://dx.doi.org/10.1038/nmeth.2684 |
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