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Potential therapeutic effects of the MTOR inhibitors for preventing ageing and progeria‐related disorders

The mammalian target of rapamycin (mTOR) pathway is an highly conserved signal transduction axis involved in many cellular processes, such as cell growth, survival, transcription, translation, apoptosis, metabolism, motility and autophagy. Recently, this signalling pathway has come to the attention...

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Detalles Bibliográficos
Autores principales: Evangelisti, Camilla, Cenni, Vittoria, Lattanzi, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061804/
https://www.ncbi.nlm.nih.gov/pubmed/26952863
http://dx.doi.org/10.1111/bcp.12928