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Potential therapeutic effects of the MTOR inhibitors for preventing ageing and progeria‐related disorders
The mammalian target of rapamycin (mTOR) pathway is an highly conserved signal transduction axis involved in many cellular processes, such as cell growth, survival, transcription, translation, apoptosis, metabolism, motility and autophagy. Recently, this signalling pathway has come to the attention...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061804/ https://www.ncbi.nlm.nih.gov/pubmed/26952863 http://dx.doi.org/10.1111/bcp.12928 |