Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition

BACKGROUND: Histone deacetylase inhibitors (HDACis) like vorinostat are promising radiosensitisers in prostate cancer, but their effect under hypoxia is not known. We investigated gene expression associated with radiosensitisation of normoxic and hypoxic prostate cancer cells by vorinostat. METHODS:...

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Detalles Bibliográficos
Autores principales: Jonsson, Marte, Ragnum, Harald Bull, Julin, Cathinka Halle, Yeramian, Andree, Clancy, Trevor, Frikstad, Kari-Anne Myrum, Seierstad, Therese, Stokke, Trond, Matias-Guiu, Xavier, Ree, Anne Hansen, Flatmark, Kjersti, Lyng, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061908/
https://www.ncbi.nlm.nih.gov/pubmed/27599042
http://dx.doi.org/10.1038/bjc.2016.278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061908/
https://www.ncbi.nlm.nih.gov/pubmed/27599042
http://dx.doi.org/10.1038/bjc.2016.278

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