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The Polymorphism −308G/A of Tumor Necrosis Factor-α Gene Modulates the Effect of Immunosuppressive Treatment in First Kidney Transplant Subjects Who Suffer an Acute Rejection

The −308G/A SNP of tumor necrosis factor-alpha (TNF-α) gene affects TNF-α production. As its impact on transplant outcome remains open to debate, we decided to genotype it in a cohort of transplant subjects. A retrospective analysis of 439 first kidney recipients randomly divided into two subgroups...

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Detalles Bibliográficos
Autores principales: Sánchez-Fructuoso, Ana Isabel, Pérez-Flores, Isabel, Valero, Rosalia, Moreno, Maria Angeles, Fernandez-Arquero, Miguel, Urcelay, Elena, Fernández-Pérez, Cristina, Santiago, Jose Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061951/
https://www.ncbi.nlm.nih.gov/pubmed/27777962
http://dx.doi.org/10.1155/2016/2197595