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The Spl Serine Proteases Modulate Staphylococcus aureus Protein Production and Virulence in a Rabbit Model of Pneumonia

The Spl proteases are a group of six serine proteases that are encoded on the νSaβ pathogenicity island and are unique to Staphylococcus aureus. Despite their interesting biochemistry, their biological substrates and functions in virulence have been difficult to elucidate. We found that an spl opero...

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Detalles Bibliográficos
Autores principales: Paharik, Alexandra E., Salgado-Pabon, Wilmara, Meyerholz, David K., White, Mark J., Schlievert, Patrick M., Horswill, Alexander R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061998/
https://www.ncbi.nlm.nih.gov/pubmed/27747296
http://dx.doi.org/10.1128/mSphere.00208-16