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The Spl Serine Proteases Modulate Staphylococcus aureus Protein Production and Virulence in a Rabbit Model of Pneumonia
The Spl proteases are a group of six serine proteases that are encoded on the νSaβ pathogenicity island and are unique to Staphylococcus aureus. Despite their interesting biochemistry, their biological substrates and functions in virulence have been difficult to elucidate. We found that an spl opero...
Autores principales: | Paharik, Alexandra E., Salgado-Pabon, Wilmara, Meyerholz, David K., White, Mark J., Schlievert, Patrick M., Horswill, Alexander R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061998/ https://www.ncbi.nlm.nih.gov/pubmed/27747296 http://dx.doi.org/10.1128/mSphere.00208-16 |
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