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In Silico Evaluation of the Impacts of Quorum Sensing Inhibition (QSI) on Strain Competition and Development of QSI Resistance

As understanding of bacterial regulatory systems and pathogenesis continues to increase, QSI has been a major focus of research. However, recent studies have shown that mechanisms of resistance to quorum sensing (QS) inhibitors (QSIs) exist, calling into question their clinical value. We propose a c...

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Detalles Bibliográficos
Autores principales: Wei, Guopeng, Lo, Chieh, Walsh, Connor, Hiller, N. Luisa, Marculescu, Radu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062075/
https://www.ncbi.nlm.nih.gov/pubmed/27734907
http://dx.doi.org/10.1038/srep35136