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The anticonvulsant retigabine suppresses neuronal K(V)2-mediated currents
Enhancement of neuronal M-currents, generated through K(V)7.2-K(V)7.5 channels, has gained much interest for its potential in developing treatments for hyperexcitability-related disorders such as epilepsy. Retigabine, a K(V)7 channel opener, has proven to be an effective anticonvulsant and has recen...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062084/ https://www.ncbi.nlm.nih.gov/pubmed/27734968 http://dx.doi.org/10.1038/srep35080 |