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The anticonvulsant retigabine suppresses neuronal K(V)2-mediated currents

Enhancement of neuronal M-currents, generated through K(V)7.2-K(V)7.5 channels, has gained much interest for its potential in developing treatments for hyperexcitability-related disorders such as epilepsy. Retigabine, a K(V)7 channel opener, has proven to be an effective anticonvulsant and has recen...

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Detalles Bibliográficos
Autores principales:	Stas, Jeroen I., Bocksteins, Elke, Jensen, Camilla S., Schmitt, Nicole, Snyders, Dirk J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062084/ https://www.ncbi.nlm.nih.gov/pubmed/27734968 http://dx.doi.org/10.1038/srep35080

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