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MicroRNA miR-204 and miR-1236 inhibit hepatitis B virus replication via two different mechanisms

Hepatitis B virus (HBV) is a major human pathogen. In this study, we found that miR-204 and miR-1236 were down-regulated in HBV-producing cells, and each could suppress HBV replication. Using a bioinformatic approach and a reporter assay, we identified miR-1236, which can reduce HBV replication and...

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Detalles Bibliográficos
Autores principales: Huang, Jyun-Yuan, Chen, Hung-Lin, Shih, Chiaho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062086/
https://www.ncbi.nlm.nih.gov/pubmed/27734898
http://dx.doi.org/10.1038/srep34740