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Microenvironment complexity and matrix stiffness regulate breast cancer cell activity in a 3D in vitro model

Three-dimensional (3D) cell cultures represent fundamental tools for the comprehension of cellular phenomena both in normal and in pathological conditions. In particular, mechanical and chemical stimuli play a relevant role on cell fate, cancer onset and malignant evolution. Here, we use mechanicall...

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Detalles Bibliográficos
Autores principales: Cavo, Marta, Fato, Marco, Peñuela, Leonardo, Beltrame, Francesco, Raiteri, Roberto, Scaglione, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062115/
https://www.ncbi.nlm.nih.gov/pubmed/27734939
http://dx.doi.org/10.1038/srep35367