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Effects of aged garlic extract and FruArg on gene expression and signaling pathways in lipopolysaccharide-activated microglial cells

Aged garlic extract (AGE) is widely used as a dietary supplement on account of its protective effects against oxidative stress and inflammation. But less is known about specific molecular targets of AGE and its bioactive components, including N-α-(1-deoxy-D-fructos-1-yl)-L-arginine (FruArg). Our rec...

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Detalles Bibliográficos
Autores principales: Song, Hailong, Lu, Yuan, Qu, Zhe, Mossine, Valeri V., Martin, Matthew B., Hou, Jie, Cui, Jiankun, Peculis, Brenda A., Mawhinney, Thomas P., Cheng, Jianlin, Greenlief, C. Michael, Fritsche, Kevin, Schmidt, Francis J., Walter, Ronald B., Lubahn, Dennis B., Sun, Grace Y., Gu, Zezong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062119/
https://www.ncbi.nlm.nih.gov/pubmed/27734935
http://dx.doi.org/10.1038/srep35323