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Effects of aged garlic extract and FruArg on gene expression and signaling pathways in lipopolysaccharide-activated microglial cells
Aged garlic extract (AGE) is widely used as a dietary supplement on account of its protective effects against oxidative stress and inflammation. But less is known about specific molecular targets of AGE and its bioactive components, including N-α-(1-deoxy-D-fructos-1-yl)-L-arginine (FruArg). Our rec...
Autores principales: | Song, Hailong, Lu, Yuan, Qu, Zhe, Mossine, Valeri V., Martin, Matthew B., Hou, Jie, Cui, Jiankun, Peculis, Brenda A., Mawhinney, Thomas P., Cheng, Jianlin, Greenlief, C. Michael, Fritsche, Kevin, Schmidt, Francis J., Walter, Ronald B., Lubahn, Dennis B., Sun, Grace Y., Gu, Zezong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062119/ https://www.ncbi.nlm.nih.gov/pubmed/27734935 http://dx.doi.org/10.1038/srep35323 |
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