Combined Transcriptomics and Chemical-Genetics Reveal Molecular Mode of Action of Valproic acid, an Anticancer Molecule using Budding Yeast Model

Valproic acid (VA) is a pharmacologically important histone deacetylase inhibitor that recently garnered attention as an anticancer agent. Since the molecular mechanisms behind the multiple effects of VA are unclear, this study was aimed to unravel the comprehensive cellular processes affected by VA...

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Detalles Bibliográficos
Autores principales: Golla, Upendarrao, Joseph, Deepthi, Tomar, Raghuvir Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062167/
https://www.ncbi.nlm.nih.gov/pubmed/27734932
http://dx.doi.org/10.1038/srep35322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062167/
https://www.ncbi.nlm.nih.gov/pubmed/27734932
http://dx.doi.org/10.1038/srep35322

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