The Role of PIK3CA Mutations among Lung Adenocarcinoma Patients with Primary and Acquired Resistance to EGFR Tyrosine Kinase Inhibition

To understand the impact of PIK3CA mutations on clinical characteristics and treatment response to epidermal growth factor tyrosine kinase inhibitors (EGFR TKIs) of lung adenocarcinoma, we examined PIK3CA and EGFR mutations in lung adenocarcinoma patients, and analyzed their clinical outcomes. Surgi...

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Detalles Bibliográficos
Autores principales: Wu, Shang-Gin, Chang, Yih-Leong, Yu, Chong-Jen, Yang, Pan-Chyr, Shih, Jin-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062358/
https://www.ncbi.nlm.nih.gov/pubmed/27734950
http://dx.doi.org/10.1038/srep35249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062358/
https://www.ncbi.nlm.nih.gov/pubmed/27734950
http://dx.doi.org/10.1038/srep35249

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