Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry

To characterize the extent and impact of ancestry-related biases in precision genomic medicine, we use 642 whole-genome sequences from the Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA) project to evaluate typical filters and databases. We find significant correlatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Kessler, Michael D., Yerges-Armstrong, Laura, Taub, Margaret A., Shetty, Amol C., Maloney, Kristin, Jeng, Linda Jo Bone, Ruczinski, Ingo, Levin, Albert M., Williams, L. Keoki, Beaty, Terri H., Mathias, Rasika A., Barnes, Kathleen C., O'Connor, Timothy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062569/
https://www.ncbi.nlm.nih.gov/pubmed/27725664
http://dx.doi.org/10.1038/ncomms12521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062569/
https://www.ncbi.nlm.nih.gov/pubmed/27725664
http://dx.doi.org/10.1038/ncomms12521

Ejemplares similares