Large-scale microfluidics providing high-resolution and high-throughput screening of Caenorhabditis elegans poly-glutamine aggregation model

Next generation drug screening could benefit greatly from in vivo studies, using small animal models such as Caenorhabditis elegans for hit identification and lead optimization. Current in vivo assays can operate either at low throughput with high resolution or with low resolution at high throughput...

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Detalles Bibliográficos
Autores principales: Mondal, Sudip, Hegarty, Evan, Martin, Chris, Gökçe, Sertan Kutal, Ghorashian, Navid, Ben-Yakar, Adela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062571/
https://www.ncbi.nlm.nih.gov/pubmed/27725672
http://dx.doi.org/10.1038/ncomms13023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062571/
https://www.ncbi.nlm.nih.gov/pubmed/27725672
http://dx.doi.org/10.1038/ncomms13023

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