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Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA

Numerous factors direct eukaryotic ribosome biogenesis, and defects in a single ribosome assembly factor may be lethal or produce tissue-specific human ribosomopathies. Pre-ribosomal RNAs (pre-rRNAs) must be processed stepwise and at the correct subcellular locations to produce the mature rRNAs. Nop...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, McCann, Kathleen L., Qiu, Chen, Gonzalez, Lauren E., Baserga, Susan J., Hall, Traci M. Tanaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062617/
https://www.ncbi.nlm.nih.gov/pubmed/27725644
http://dx.doi.org/10.1038/ncomms13085