Increased global transcription activity as a mechanism of replication stress in cancer

Cancer is a disease associated with genomic instability that often results from oncogene activation. This in turn leads to hyperproliferation and replication stress. However, the molecular mechanisms that underlie oncogene-induced replication stress are still poorly understood. Oncogenes such as HRA...

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Detalles Bibliográficos
Autores principales: Kotsantis, Panagiotis, Silva, Lara Marques, Irmscher, Sarah, Jones, Rebecca M., Folkes, Lisa, Gromak, Natalia, Petermann, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062618/
https://www.ncbi.nlm.nih.gov/pubmed/27725641
http://dx.doi.org/10.1038/ncomms13087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062618/
https://www.ncbi.nlm.nih.gov/pubmed/27725641
http://dx.doi.org/10.1038/ncomms13087

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