Fumarate modulates the immune/inflammatory response and rescues nerve cells and neurological function after stroke in rats

BACKGROUND: Dimethyl fumarate (DMF), working via its metabolite monomethylfumarate (MMF), acts as a potent antioxidant and immunomodulator in animal models of neurologic disease and in patients with multiple sclerosis. These properties and their translational potential led us to investigate whether...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Ruihe, Cai, Jingli, Kostuk, Eric W., Rosenwasser, Robert, Iacovitti, Lorraine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062839/
https://www.ncbi.nlm.nih.gov/pubmed/27733178
http://dx.doi.org/10.1186/s12974-016-0733-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062839/
https://www.ncbi.nlm.nih.gov/pubmed/27733178
http://dx.doi.org/10.1186/s12974-016-0733-1

Ejemplares similares