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Fumarate modulates the immune/inflammatory response and rescues nerve cells and neurological function after stroke in rats
BACKGROUND: Dimethyl fumarate (DMF), working via its metabolite monomethylfumarate (MMF), acts as a potent antioxidant and immunomodulator in animal models of neurologic disease and in patients with multiple sclerosis. These properties and their translational potential led us to investigate whether...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062839/ https://www.ncbi.nlm.nih.gov/pubmed/27733178 http://dx.doi.org/10.1186/s12974-016-0733-1 |