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Over-expression of the long non-coding RNA HOTTIP inhibits glioma cell growth by BRE

BACKGROUND: Gliomas are the most common type of primary brain tumour in the central nervous system of adults. The long non-coding RNA (lncRNA) HOXA transcript at the distal tip (HOTTIP) is transcribed from the 5′ tip of the HOXA locus. HOTTIP has recently been shown to be dysregulated and play an im...

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Detalles Bibliográficos
Autores principales: Xu, Li-Min, Chen, Lei, Li, Feng, Zhang, Run, Li, Zong-yang, Chen, Fan-Fan, Jiang, Xiao-Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062847/
https://www.ncbi.nlm.nih.gov/pubmed/27733185
http://dx.doi.org/10.1186/s13046-016-0431-y