Inactivation of the tumor suppressor gene von Hippel-Lindau (VHL) in granulocytes contributes to development of liver hemangiomas in a mouse model

BACKGROUND: Mutations in the tumor suppressor gene von Hippel-Lindau (VHL) underlie a hereditary cancer syndrome—VHL disease—and are also frequently observed in sporadic renal cell carcinoma of the clear cell type (ccRCC). VHL disease is characterized by malignant and benign tumors in a few specific...

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Detalles Bibliográficos
Autores principales: Bader, Hannah L., Hsu, Tien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062848/
https://www.ncbi.nlm.nih.gov/pubmed/27733136
http://dx.doi.org/10.1186/s12885-016-2802-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062848/
https://www.ncbi.nlm.nih.gov/pubmed/27733136
http://dx.doi.org/10.1186/s12885-016-2802-3

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