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The chimeric multi-domain proteins mediating specific DNA transfer for hepatocellular carcinoma treatment

AIM: This study was aimed to evaluate the therapeutic efficiency of a non-virus based specific chimeric multi-domain DNA transferred with apoptin in human hepatocellular carcinoma (HCC) HepG-2 cells in vitro and in mice H22 cells in vivo. METHODS: We firstly constructed the multi-domain recombinant...

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Detalles Bibliográficos
Autores principales: Yang, Encheng, Li, Xiao, Jin, Ningyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062862/
https://www.ncbi.nlm.nih.gov/pubmed/27752239
http://dx.doi.org/10.1186/s12935-016-0351-0