Designer Leptin Receptor Antagonist Allo-aca Inhibits VEGF Effects in Ophthalmic Neoangiogenesis Models

Experimental and clinical data suggest that pro-angiogenic, pro-inflammatory and mitogenic cytokine leptin can be implicated in ocular neovascularization and other eye pathologies. At least in part, leptin action appears to be mediated through functional interplay with vascular endothelial growth fa...

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Detalles Bibliográficos
Autores principales: Coroniti, Roberta, Farjo, Rafal, Nuno, Didier J., Otvos, Laszlo, Scolaro, Laura, Surmacz, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062870/
https://www.ncbi.nlm.nih.gov/pubmed/27790618
http://dx.doi.org/10.3389/fmolb.2016.00067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062870/
https://www.ncbi.nlm.nih.gov/pubmed/27790618
http://dx.doi.org/10.3389/fmolb.2016.00067

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