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Emergence of heterogeneity in acute leukemias

BACKGROUND: Leukemias are malignant proliferative disorders of the blood forming system. Sequencing studies demonstrate that the leukemic cell population consists of multiple clones. The genetic relationship between the different clones, referred to as the clonal hierarchy, shows high interindividua...

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Detalles Bibliográficos
Autores principales: Stiehl, Thomas, Lutz, Christoph, Marciniak-Czochra, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062896/
https://www.ncbi.nlm.nih.gov/pubmed/27733173
http://dx.doi.org/10.1186/s13062-016-0154-1