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Maternal vitamin D depletion alters DNA methylation at imprinted loci in multiple generations

BACKGROUND: Environmental perturbation of epigenetic mechanisms is linked to a growing number of diseases. Characterizing the role environmental factors play in modifying the epigenome is important for disease etiology. Vitamin D is an essential nutrient affecting brain, bone, heart, immune and repr...

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Detalles Bibliográficos
Autores principales: Xue, Jing, Schoenrock, Sarah A., Valdar, William, Tarantino, Lisa M., Ideraabdullah, Folami Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062906/
https://www.ncbi.nlm.nih.gov/pubmed/27777636
http://dx.doi.org/10.1186/s13148-016-0276-4