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An HIV-1 capsid binding protein TRIM11 accelerates viral uncoating

BACKGROUND: Several members of the TRIM family have been implicated in antiviral defense. Our previous report showed that human TRIM11 potently inhibited HIV-1 transduction by reducing the viral reverse transcripts. These results prompted us to examine the effect of TRIM11 on HIV-1 uncoating, which...

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Detalles Bibliográficos
Autores principales: Yuan, Ting, Yao, Weitong, Tokunaga, Kenzo, Yang, Rongge, Sun, Binlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062926/
https://www.ncbi.nlm.nih.gov/pubmed/27737691
http://dx.doi.org/10.1186/s12977-016-0306-5