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Global DNA methylation profiling reveals new insights into epigenetically deregulated protein coding and long noncoding RNAs in CLL

BACKGROUND: Methyl-CpG-binding domain protein enriched genome-wide sequencing (MBD-Seq) is a robust and powerful method for analyzing methylated CpG-rich regions with complete genome-wide coverage. In chronic lymphocytic leukemia (CLL), the role of CpG methylated regions associated with transcribed...

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Detalles Bibliográficos
Autores principales: Subhash, Santhilal, Andersson, Per-Ola, Kosalai, Subazini Thankaswamy, Kanduri, Chandrasekhar, Kanduri, Meena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062931/
https://www.ncbi.nlm.nih.gov/pubmed/27777635
http://dx.doi.org/10.1186/s13148-016-0274-6