Differential sensitivity to methylated DNA by ETS-family transcription factors is intrinsically encoded in their DNA-binding domains

Transactivation by the ETS family of transcription factors, whose members share structurally conserved DNA-binding domains, is variably sensitive to methylation of their target genes. The mechanism by which DNA methylation controls ETS proteins remains poorly understood. Uncertainly also pervades th...

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Detalles Bibliográficos
Autores principales: Stephens, Dominique C., Poon, Gregory M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062964/
https://www.ncbi.nlm.nih.gov/pubmed/27270080
http://dx.doi.org/10.1093/nar/gkw528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062964/
https://www.ncbi.nlm.nih.gov/pubmed/27270080
http://dx.doi.org/10.1093/nar/gkw528

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