G-quadruplex recognition and remodeling by the FANCJ helicase

Guanine rich nucleic acid sequences can form G-quadruplex (G4) structures that interfere with DNA replication, repair and RNA transcription. The human FANCJ helicase contributes to maintaining genomic integrity by promoting DNA replication through G4-forming DNA regions. Here, we combined single-mol...

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Detalles Bibliográficos
Autores principales: Wu, Colin G., Spies, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062972/
https://www.ncbi.nlm.nih.gov/pubmed/27342280
http://dx.doi.org/10.1093/nar/gkw574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062972/
https://www.ncbi.nlm.nih.gov/pubmed/27342280
http://dx.doi.org/10.1093/nar/gkw574

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