High-temperature single-molecule kinetic analysis of thermophilic archaeal MCM helicases

The minichromosome maintenance (MCM) complex is the replicative helicase responsible for unwinding DNA during archaeal and eukaryal genome replication. To mimic long helicase events in the cell, a high-temperature single-molecule assay was designed to quantitatively measure long-range DNA unwinding...

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Detalles Bibliográficos
Autores principales: Schermerhorn, Kelly M., Tanner, Nathan, Kelman, Zvi, Gardner, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062978/
https://www.ncbi.nlm.nih.gov/pubmed/27382065
http://dx.doi.org/10.1093/nar/gkw612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062978/
https://www.ncbi.nlm.nih.gov/pubmed/27382065
http://dx.doi.org/10.1093/nar/gkw612

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