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Human CDK18 promotes replication stress signaling and genome stability

Cyclin-dependent kinases (CDKs) coordinate cell cycle checkpoints with DNA repair mechanisms that together maintain genome stability. However, the myriad mechanisms that can give rise to genome instability are still to be fully elucidated. Here, we identify CDK18 (PCTAIRE 3) as a novel regulator of...

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Detalles Bibliográficos
Autores principales: Barone, Giancarlo, Staples, Christopher J., Ganesh, Anil, Patterson, Karl W., Bryne, Dominic P., Myers, Katie N., Patil, Abhijit A., Eyers, Claire E., Maslen, Sarah, Skehel, J. Mark, Eyers, Patrick A., Collis, Spencer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062979/
https://www.ncbi.nlm.nih.gov/pubmed/27382066
http://dx.doi.org/10.1093/nar/gkw615