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Multiple consecutive initiation of replication producing novel brush-like intermediates at the termini of linear viral dsDNA genomes with hairpin ends

Linear dsDNA replicons with hairpin ends are found in the three domains of life, mainly associated with plasmids and viruses including the poxviruses, some phages and archaeal rudiviruses. However, their replication mechanism is not clearly understood. In this study, we find that the rudivirus SIRV2...

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Detalles Bibliográficos
Autores principales: Martínez-Alvarez, Laura, Bell, Stephen D., Peng, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062984/
https://www.ncbi.nlm.nih.gov/pubmed/27407114
http://dx.doi.org/10.1093/nar/gkw636