Force and twist dependence of RepC nicking activity on torsionally-constrained DNA molecules

Many bacterial plasmids replicate by an asymmetric rolling-circle mechanism that requires sequence-specific recognition for initiation, nicking of one of the template DNA strands and unwinding of the duplex prior to subsequent leading strand DNA synthesis. Nicking is performed by a replication-initi...

Descripción completa

Detalles Bibliográficos
Autores principales: Pastrana, Cesar L., Carrasco, Carolina, Akhtar, Parvez, Leuba, Sanford H., Khan, Saleem A., Moreno-Herrero, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062986/
https://www.ncbi.nlm.nih.gov/pubmed/27488190
http://dx.doi.org/10.1093/nar/gkw689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062986/
https://www.ncbi.nlm.nih.gov/pubmed/27488190
http://dx.doi.org/10.1093/nar/gkw689

Ejemplares similares