Mitochondrial DNA exhibits resistance to induced point and deletion mutations

The accumulation of somatic mitochondrial DNA (mtDNA) mutations contributes to the pathogenesis of human disease. Currently, mitochondrial mutations are largely considered results of inaccurate processing of its heavily damaged genome. However, mainly from a lack of methods to monitor mtDNA mutation...

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Detalles Bibliográficos
Autores principales: Valente, William J., Ericson, Nolan G., Long, Alexandra S., White, Paul A., Marchetti, Francesco, Bielas, Jason H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062989/
https://www.ncbi.nlm.nih.gov/pubmed/27550180
http://dx.doi.org/10.1093/nar/gkw716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062989/
https://www.ncbi.nlm.nih.gov/pubmed/27550180
http://dx.doi.org/10.1093/nar/gkw716

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