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Mitochondrial DNA exhibits resistance to induced point and deletion mutations
The accumulation of somatic mitochondrial DNA (mtDNA) mutations contributes to the pathogenesis of human disease. Currently, mitochondrial mutations are largely considered results of inaccurate processing of its heavily damaged genome. However, mainly from a lack of methods to monitor mtDNA mutation...
Autores principales: | Valente, William J., Ericson, Nolan G., Long, Alexandra S., White, Paul A., Marchetti, Francesco, Bielas, Jason H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062989/ https://www.ncbi.nlm.nih.gov/pubmed/27550180 http://dx.doi.org/10.1093/nar/gkw716 |
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