Rational design of a synthetic mammalian riboswitch as a ligand-responsive -1 ribosomal frame-shifting stimulator

Metabolite-responsive RNA pseudoknots derived from prokaryotic riboswitches have been shown to stimulate −1 programmed ribosomal frameshifting (PRF), suggesting −1 PRF as a promising gene expression platform to extend riboswitch applications in higher eukaryotes. However, its general application has...

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Detalles Bibliográficos
Autores principales: Lin, Ya-Hui, Chang, Kung-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062990/
https://www.ncbi.nlm.nih.gov/pubmed/27521370
http://dx.doi.org/10.1093/nar/gkw718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062990/
https://www.ncbi.nlm.nih.gov/pubmed/27521370
http://dx.doi.org/10.1093/nar/gkw718

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