Using NMR and molecular dynamics to link structure and dynamics effects of the universal base 8-aza, 7-deaza, N8 linked adenosine analog

A truly universal nucleobase enables a host of novel applications such as simplified templates for PCR primers, randomized sequencing and DNA based devices. A universal base must pair indiscriminately to each of the canonical bases with little or preferably no destabilization of the overall duplex....

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Detalles Bibliográficos
Autores principales: Spring-Connell, Alexander M., Evich, Marina G., Debelak, Harald, Seela, Frank, Germann, Markus W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062995/
https://www.ncbi.nlm.nih.gov/pubmed/27566150
http://dx.doi.org/10.1093/nar/gkw736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062995/
https://www.ncbi.nlm.nih.gov/pubmed/27566150
http://dx.doi.org/10.1093/nar/gkw736

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