Cargando…

Tumor suppressor protein DAB2IP participates in chromosomal stability maintenance through activating spindle assembly checkpoint and stabilizing kinetochore-microtubule attachments

Defects in kinetochore-microtubule (KT-MT) attachment and the spindle assembly checkpoint (SAC) during cell division are strongly associated with chromosomal instability (CIN). CIN has been linked to carcinogenesis, metastasis, poor prognosis and resistance to cancer therapy. We previously reported...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Lan, Shang, Zeng-Fu, Abdisalaam, Salim, Lee, Kyung-Jong, Gupta, Arun, Hsieh, Jer-Tsong, Asaithamby, Aroumougame, Chen, Benjamin P.C., Saha, Debabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062997/
https://www.ncbi.nlm.nih.gov/pubmed/27568005
http://dx.doi.org/10.1093/nar/gkw746