Cargando…

Deficient glucose and glutamine metabolism in Aralar/AGC1/Slc25a12 knockout mice contributes to altered visual function

PURPOSE: To characterize the vision phenotype of mice lacking Aralar/AGC1/Slc25a12, the mitochondrial aspartate-glutamate carrier mutated in global cerebral hypomyelination (OMIM 612949). METHODS: We tested overnight dark-adapted control and aralar-deficient mice for the standard full electroretinog...

Descripción completa

Detalles Bibliográficos
Autores principales: Contreras, Laura, Ramirez, Laura, Du, Jianhai, Hurley, James B., Satrústegui, Jorgina, de la Villa, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063090/
https://www.ncbi.nlm.nih.gov/pubmed/27746674