Cross‐disease comparison of amyotrophic lateral sclerosis and spinal muscular atrophy reveals conservation of selective vulnerability but differential neuromuscular junction pathology

Neuromuscular junctions are primary pathological targets in the lethal motor neuron diseases spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS). Synaptic pathology and denervation of target muscle fibers has been reported prior to the appearance of clinical symptoms in mouse model...

Descripción completa

Detalles Bibliográficos
Autores principales: Comley, Laura H., Nijssen, Jik, Frost‐Nylen, Johanna, Hedlund, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063101/
https://www.ncbi.nlm.nih.gov/pubmed/26502195
http://dx.doi.org/10.1002/cne.23917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063101/
https://www.ncbi.nlm.nih.gov/pubmed/26502195
http://dx.doi.org/10.1002/cne.23917

Ejemplares similares