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IgM‐enriched solution BT086 improves host defense capacity and energy store preservation in a rabbit model of endotoxemia

INTRODUCTION: The therapeutic value of intravenous immunoglobulin (IVIG) as an adjuvant therapy in sepsis remains debatable. We hypothesized that intravenous administration of BT086, a predominantly IgM IVIG solution, would improve host defense in an established rabbit model of endotoxemia and syste...

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Detalles Bibliográficos
Autores principales: Shmygalev, S., Damm, M., Knels, L., Strassburg, A., Wünsche, K., Dumke, R., Stehr, S. N., Koch, T., Heller, A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063102/
https://www.ncbi.nlm.nih.gov/pubmed/26555358
http://dx.doi.org/10.1111/aas.12652