Cargando…

IgM‐enriched solution BT086 improves host defense capacity and energy store preservation in a rabbit model of endotoxemia

INTRODUCTION: The therapeutic value of intravenous immunoglobulin (IVIG) as an adjuvant therapy in sepsis remains debatable. We hypothesized that intravenous administration of BT086, a predominantly IgM IVIG solution, would improve host defense in an established rabbit model of endotoxemia and syste...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shmygalev, S., Damm, M., Knels, L., Strassburg, A., Wünsche, K., Dumke, R., Stehr, S. N., Koch, T., Heller, A. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Intensive Care and Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063102/ https://www.ncbi.nlm.nih.gov/pubmed/26555358 http://dx.doi.org/10.1111/aas.12652

Ejemplares similares

Adjunctive IgM-enriched immunoglobulin therapy with a personalised dose based on serum IgM-titres versus standard dose in the treatment of septic shock: a randomised controlled trial (IgM-fat trial)
por: Biagioni, Emanuela, et al.
Publicado: (2021)

Interrogating a clinical database to study treatment of hypotension in the critically ill
por: Lee, Joon, et al.
Publicado: (2012)

Protocol: inspiratory muscle training for promoting recovery and outcomes in ventilated patients (IMPROVe): a randomised controlled trial
por: Bissett, Bernie M, et al.
Publicado: (2012)

Effect of intravenous GLutamine supplementation IN Trauma patients receiving enteral nutrition study protocol (GLINT Study): a prospective, blinded, randomised, placebo-controlled clinical trial
por: Al Balushi, Ruqaiya M, et al.
Publicado: (2011)

Accuracy of LightCycler® SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review protocol
por: Dark, Paul, et al.
Publicado: (2012)

A longitudinal qualitative exploration of healthcare and informal support needs among survivors of critical illness: the RELINQUISH protocol
por: Ramsay, Pam, et al.
Publicado: (2012)

A randomised controlled trial evaluating a rehabilitation complex intervention for patients following intensive care discharge: the RECOVER study
por: Walsh, Timothy Simon, et al.
Publicado: (2012)

Relevance of anxiety in clinical practice of Guillain-Barré syndrome: a cohort study
por: Sharshar, Tarek, et al.
Publicado: (2012)

Early rehabilitation in critical care (eRiCC): functional electrical stimulation with cycling protocol for a randomised controlled trial
por: Parry, Selina M, et al.
Publicado: (2012)

Procalcitonin levels to guide antibiotic therapy in adults with non-microbiologically proven apparent severe sepsis: a randomised controlled trial
por: Annane, Djillali, et al.
Publicado: (2013)

Adverse drug events in a paediatric intensive care unit: a prospective cohort
por: Silva, Dafne C B, et al.
Publicado: (2013)

A UK survey of rehabilitation following critical illness: implementation of NICE Clinical Guidance 83 (CG83) following hospital discharge
por: Connolly, Bronwen, et al.
Publicado: (2014)

Lactate clearance as a useful biomarker for the prediction of all-cause mortality in critically ill patients: a systematic review study protocol
por: Zhang, Zhongheng, et al.
Publicado: (2014)

IMPOSE (IMProving Outcomes after Sepsis)—the effect of a multidisciplinary follow-up service on health-related quality of life in patients postsepsis syndromes—a double-blinded randomised controlled trial: protocol
por: Paratz, Jennifer D, et al.
Publicado: (2014)

Effect of supervised aerobic exercise rehabilitation on physical fitness and quality-of-life in survivors of critical illness: an exploratory minimized controlled trial (PIX study)
por: Batterham, A. M., et al.
Publicado: (2014)

Recombinant human activated protein C for the treatment of severe sepsis and septic shock: a study protocol for incorporating observational evidence using a Bayesian approach
por: Zhang, Zhongheng
Publicado: (2014)

Short-term use of remifentanil during endotracheal extubation for prophylactic analgesia in neurosurgical patients after craniotomy (SURE after Craniotomy Study): a study protocol and statistical analysis plan for a randomised controlled trial
por: Wu, Yuan-Xing, et al.
Publicado: (2014)

Cost-effectiveness of a quality improvement programme to reduce central line-associated bloodstream infections in intensive care units in the USA
por: Herzer, Kurt R, et al.
Publicado: (2014)

The Esophageal Pressure-Guided Ventilation 2 (EPVent2) trial protocol: a multicentre, randomised clinical trial of mechanical ventilation guided by transpulmonary pressure
por: Fish, Emily, et al.
Publicado: (2014)

Comparison of Enteral versus Intravenous Potassium Supplementation in hypokalaemia in postcardiac surgery paediatric cardiac intensive care patients: prospective open label randomised control trial (EIPS)
por: Merchant, Quratulain, et al.
Publicado: (2014)

The General Weakness Syndrome Therapy (GymNAST) study: protocol for a cohort study on recovery on walking function
por: Mehrholz, Jan, et al.
Publicado: (2014)

Procalcitonin as a predictor of moderate to severe acute respiratory distress syndrome after cardiac surgery with cardiopulmonary bypass: a study protocol for a prospective cohort study
por: Chen, Han, et al.
Publicado: (2014)

Identifying intensive care unit discharge planning tools: protocol for a scoping review
por: Stelfox, Henry T, et al.
Publicado: (2013)

A study protocol for performance evaluation of a new academic intensive care unit facility: impact on patient care
por: Ferri, Mauricio, et al.
Publicado: (2013)

Surgical Intensive Care Unit Optimal Mobilisation Score (SOMS) trial: a protocol for an international, multicentre, randomised controlled trial focused on goal-directed early mobilisation of surgical ICU patients
por: Meyer, Matthew J, et al.
Publicado: (2013)

The proportion of clinically relevant alarms decreases as patient clinical severity decreases in intensive care units: a pilot study
por: Inokuchi, Ryota, et al.
Publicado: (2013)

Ten years of asthma admissions to adult critical care units in England and Wales
por: Gibbison, Ben, et al.
Publicado: (2013)

Efficacy of coupled plasma filtration adsorption (CPFA) in patients with septic shock: A multicenter randomised controlled clinical trial
por: Livigni, Sergio, et al.
Publicado: (2014)

Extra Physiotherapy in Critical Care (EPICC) Trial Protocol: a randomised controlled trial of intensive versus standard physical rehabilitation therapy in the critically ill
por: Thomas, Kirsty, et al.
Publicado: (2015)

Hospital costs of out-of-hospital cardiac arrest patients treated in intensive care; a single centre evaluation using the national tariff-based system
por: Petrie, J, et al.
Publicado: (2015)

Emergence agitation during recovery from intracranial surgery under general anaesthesia: a protocol and statistical analysis plan for a prospective multicentre cohort study
por: Yan, Li-Mei, et al.
Publicado: (2015)

Biomarkers of necrotising soft tissue infections: aspects of the innate immune response and effects of hyperbaric oxygenation—the protocol of the prospective cohort BIONEC study
por: Hansen, Marco Bo, et al.
Publicado: (2015)

Prospective cohort study protocol to describe the transfer of patients from intensive care units to hospital wards
por: Buchner, Denise L, et al.
Publicado: (2015)

The Deyo-Charlson and Elixhauser-van Walraven Comorbidity Indices as predictors of mortality in critically ill patients
por: Ladha, Karim S, et al.
Publicado: (2015)

How do doctors and nurses manage delirium in intensive care units? A qualitative study using focus groups
por: Palacios-Ceña, Domingo, et al.
Publicado: (2016)

Identifying low-value clinical practices in critical care medicine: protocol for a scoping review
por: Niven, Daniel J, et al.
Publicado: (2015)

Incidence of ventilator-associated pneumonia in Australasian intensive care units: use of a consensus-developed clinical surveillance checklist in a multisite prospective audit
por: Elliott, Doug, et al.
Publicado: (2015)

Evaluating the feasibility and effectiveness of a critical care discharge information pack for patients and their families: a pilot cluster randomised controlled trial
por: Bench, Suzanne, et al.
Publicado: (2015)

Changes in health-related quality of life (HRQoL) after discharge from intensive care unit: a protocol for a systematic review
por: Gerth, Alice M J, et al.
Publicado: (2015)

Validation and optimisation of an ICD-10-coded case definition for sepsis using administrative health data
por: Jolley, Rachel J, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ecrkfh5m0t25f7rafta68rdq9u