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A thorough QTc study demonstrates that olmesartan medoxomil does not prolong the QTc interval

Two studies (ROADMAP and ORIENT) evaluating the renoprotective effects of olmesartan medoxomil (OM) in patients with type 2 diabetes suggested OM is associated with increased cardiovascular mortality. We conducted a thorough QTc study to evaluate the effects of OM on cardiac repolarization. A random...

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Detalles Bibliográficos
Autores principales: Mendell, Jeanne, Matsushima, Nobuko, O'Reilly, Terry E., Lee, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063153/
https://www.ncbi.nlm.nih.gov/pubmed/26239632
http://dx.doi.org/10.1002/jcph.610