Engineered fibroblast growth factor 19 reduces liver injury and resolves sclerosing cholangitis in Mdr2‐deficient mice

Defects in multidrug resistance 3 gene (MDR3), which encodes the canalicular phospholipid flippase, cause a wide spectrum of cholangiopathy phenotypes in humans. Mice deficient in Mdr2 (murine ortholog of MDR3) develop liver diseases that closely reproduce the biochemical, histological, and clinical...

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Detalles Bibliográficos
Autores principales: Zhou, Mei, Learned, R. Marc, Rossi, Stephen J., DePaoli, Alex M., Tian, Hui, Ling, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Autoimmune, Cholestatic and Biliary Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063176/
https://www.ncbi.nlm.nih.gov/pubmed/26418580
http://dx.doi.org/10.1002/hep.28257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063176/
https://www.ncbi.nlm.nih.gov/pubmed/26418580
http://dx.doi.org/10.1002/hep.28257

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