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Severe Changes in Thymic Microenvironment in a Chronic Experimental Model of Paracoccidioidomycosis
T cell maturation takes place within the thymus, a primary lymphoid organ that is commonly targeted during infections. Previous studies showed that acute infection with Paracoccidioides brasiliensis (Pb), the causative agent of paracoccidioidomycosis (PCM), promotes thymic atrophy that is associated...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063316/ https://www.ncbi.nlm.nih.gov/pubmed/27736987 http://dx.doi.org/10.1371/journal.pone.0164745 |