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Maturation of the Intestinal Epithelial Barrier in Neonatal Rats Coincides with Decreased FcRn Expression, Replacement of Vacuolated Enterocytes and Changed Blimp-1 Expression

BACKGROUND: The intestinal barrier is immature in newborn mammals allowing for transfer of bioactive macromolecules, e.g. protecting antibodies, from mother’s milk to the blood circulation and in neonatal rodents lasts until weaning. This passage involves the neonatal-Fc-receptor (FcRn) binding IgG...

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Detalles Bibliográficos
Autores principales: Arévalo Sureda, Ester, Weström, Björn, Pierzynowski, Stefan G., Prykhodko, Olena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063338/
https://www.ncbi.nlm.nih.gov/pubmed/27736989
http://dx.doi.org/10.1371/journal.pone.0164775