Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson’s Disease

We have been investigating the role that phosphatidylethanolamine (PE) and phosphatidylcholine (PC) content plays in modulating the solubility of the Parkinson’s disease protein alpha-synuclein (α-syn) using Saccharomyces cerevisiae and Caenorhabditis elegans. One enzyme that synthesizes PE is the c...

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Detalles Bibliográficos
Autores principales: Wang, Shaoxiao, Zhang, Siyuan, Xu, Chuan, Barron, Addie, Galiano, Floyd, Patel, Dhaval, Lee, Yong Joo, Caldwell, Guy A., Caldwell, Kim A., Witt, Stephan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063346/
https://www.ncbi.nlm.nih.gov/pubmed/27736935
http://dx.doi.org/10.1371/journal.pone.0164465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063346/
https://www.ncbi.nlm.nih.gov/pubmed/27736935
http://dx.doi.org/10.1371/journal.pone.0164465

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